Security December 15, 2025 12 min read

On-Premise LLM Deployment: Llama 3 vs Mistral

Benchmarks and deployment patterns for running local LLMs in enterprise environments where data cannot leave your infrastructure.

For enterprises handling sensitive data—financial records, healthcare information, proprietary code—sending prompts to external APIs is often not an option. The solution: run the LLM on your own infrastructure. But which model, and how?

Why On-Premise?

Before diving into benchmarks, let's be clear about when on-premise deployment makes sense:

If none of these apply, cloud APIs (OpenAI, Anthropic with EU data residency) are simpler and often sufficient.

The Contenders

We evaluated the two leading open-weight models for enterprise deployment:

Llama 3.1 70B
Meta AI
  • • 70 billion parameters
  • • 128k context window
  • • Strong reasoning capabilities
  • • Permissive license for commercial use
Mistral Large 2
Mistral AI
  • • 123 billion parameters
  • • 128k context window
  • • Excellent instruction following
  • • EU-based company (GDPR alignment)

Hardware Requirements

Running these models requires serious GPU power. Here's what we tested:

Configuration Llama 3.1 70B Mistral Large 2
Minimum VRAM 140GB (FP16) 246GB (FP16)
Quantized (INT8) 70GB 123GB
Quantized (INT4) 35GB 62GB
Recommended Setup 2x A100 80GB 4x A100 80GB
Cost Reality Check: A production-grade 4x A100 server runs $150,000-200,000. For most enterprises, cloud GPU instances (AWS p4d, Azure NC A100) are more practical until inference volume justifies the capex.

Performance Benchmarks

We ran benchmarks on identical hardware (4x A100 80GB, NVLink) using vLLM for inference optimization:

Throughput (tokens/second) - Batch Size 32
Llama 3.1 70B (INT8) 1,847 tok/s
Mistral Large 2 (INT8) 1,423 tok/s
Latency (Time to First Token) - Single Request
89ms
Llama 3.1 70B
112ms
Mistral Large 2

Quality Comparison

For our engineering use cases (document analysis, code review, incident triage), we evaluated on task-specific benchmarks:

Task Llama 3.1 70B Mistral Large 2
Contract clause extraction 91.2% 94.7%
Code vulnerability detection 87.3% 85.1%
Log anomaly classification 89.5% 91.2%
Instruction following 88.1% 93.4%

Our Recommendation

For Most Enterprise Use Cases: Llama 3.1 70B

Better throughput, lower hardware requirements, and competitive quality. The permissive license makes it easier for legal approval. Use INT8 quantization for the best quality/speed tradeoff.

For Complex Reasoning Tasks: Mistral Large 2

If instruction following and nuanced document understanding are critical, Mistral's edge is worth the extra hardware. EU headquarters is a plus for GDPR-sensitive industries.

Deployment Architecture

Here's our recommended production stack for on-premise LLM deployment:

docker-compose.yml
services:
  vllm:
    image: vllm/vllm-openai:latest
    deploy:
      resources:
        reservations:
          devices:
            - driver: nvidia
              count: 4
              capabilities: [gpu]
    environment:
      - MODEL=meta-llama/Llama-3.1-70B-Instruct
      - QUANTIZATION=awq
      - MAX_MODEL_LEN=32768
    ports:
      - "8000:8000"

  vector-db:
    image: qdrant/qdrant:latest
    volumes:
      - qdrant_data:/qdrant/storage

  agent-orchestrator:
    image: aixagent/orchestrator:latest
    depends_on:
      - vllm
      - vector-db
    environment:
      - LLM_ENDPOINT=http://vllm:8000/v1
      - VECTOR_DB=http://vector-db:6333

Security Considerations

  1. Network isolation

    Run LLM inference in a private subnet with no internet egress. All communication via internal load balancer.

  2. Audit logging

    Log all prompts and responses (encrypted at rest) for compliance and debugging.

  3. Input sanitization

    Filter prompts for prompt injection attempts before they reach the model.

  4. Access control

    Use API keys and rate limiting. Consider per-team token budgets.

Conclusion

On-premise LLM deployment is now practical for enterprises willing to invest in GPU infrastructure. For most use cases, Llama 3.1 70B with INT8 quantization offers the best balance of performance, quality, and hardware efficiency.

The key is matching your deployment choice to your actual requirements. Not everyone needs the largest model—and not everyone needs on-premise at all. Start with your data sensitivity and latency requirements, then work backward to the right architecture.

Need help deploying on-premise LLMs?

We design and deploy private AI infrastructure for enterprises with strict data requirements.

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